微生物组构成中的大规模扰动与人类生理的健康和功能密切相关，无论是驱动力还是后果。但是，由于微生物之间的大量复杂相互作用，了解健康和疾病个体的微生物组轮廓的差异可能会变得复杂。我们建议将这些相互作用建模为随时间变化的图，其节点是微生物，边缘是它们之间的相互作用。由于需要分析这种复杂的相互作用的需要，我们开发了一种方法，该方法可以学习时间不断发展的图表的低维表示，并保持在高维空间中发生的动力学。通过我们的实验，我们表明我们可以提取图形特征，例如节点簇或边缘簇，这些节点或边缘对模型具有最大影响，以学习低维表示。这些信息对于鉴定与临床疾病密切相关的微生物以及它们之间的相互作用至关重要。我们对合成和现实世界微生物组数据集进行了实验。

ICECUBE是一种用于检测1 GEV和1 PEV之间大气和天体中微子的光学传感器的立方公斤阵列，该阵列已部署1.45 km至2.45 km的南极的冰盖表面以下1.45 km至2.45 km。来自ICE探测器的事件的分类和重建在ICeCube数据分析中起着核心作用。重建和分类事件是一个挑战，这是由于探测器的几何形状，不均匀的散射和冰中光的吸收，并且低于100 GEV的光，每个事件产生的信号光子数量相对较少。为了应对这一挑战，可以将ICECUBE事件表示为点云图形，并将图形神经网络（GNN）作为分类和重建方法。 GNN能够将中微子事件与宇宙射线背景区分开，对不同的中微子事件类型进行分类，并重建沉积的能量，方向和相互作用顶点。基于仿真，我们提供了1-100 GEV能量范围的比较与当前ICECUBE分析中使用的当前最新最大似然技术，包括已知系统不确定性的影响。对于中微子事件分类，与当前的IceCube方法相比，GNN以固定的假阳性速率（FPR）提高了信号效率的18％。另外，GNN在固定信号效率下将FPR的降低超过8（低于半百分比）。对于能源，方向和相互作用顶点的重建，与当前最大似然技术相比，分辨率平均提高了13％-20％。当在GPU上运行时，GNN能够以几乎是2.7 kHz的中位数ICECUBE触发速率的速率处理ICECUBE事件，这打开了在在线搜索瞬态事件中使用低能量中微子的可能性。

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Neural networks have revolutionized the area of artificial intelligence and introduced transformative applications to almost every scientific field and industry. However, this success comes at a great price; the energy requirements for training advanced models are unsustainable. One promising way to address this pressing issue is by developing low-energy neuromorphic hardware that directly supports the algorithm's requirements. The intrinsic non-volatility, non-linearity, and memory of spintronic devices make them appealing candidates for neuromorphic devices. Here we focus on the reservoir computing paradigm, a recurrent network with a simple training algorithm suitable for computation with spintronic devices since they can provide the properties of non-linearity and memory. We review technologies and methods for developing neuromorphic spintronic devices and conclude with critical open issues to address before such devices become widely used.

The deployment of neural networks on heterogeneous SoCs coupled with custom accelerators is a challenging task because of the lack of end-to-end software tools provided for these systems. Moreover, the already available low level schedules and mapping strategies provided by the accelerator developers for typical tensor operations are not necessarily the best possible ones for each particular use case. This is why frameworks which automatically test the performance of the generated code on a specific hardware configuration are of special interest. In this work, the integration between the code generation framework TVM and the systolic array-based accelerator Gemmini is presented. A generic schedule to offload the GEneral Matrix Multiply (GEMM) tensor operation onto Gemmini is detailed, and its suitability is tested by executing the AutoTVM tuning process on it. Our generated code achieves a peak throughput of 46 giga-operations per second (GOPs) under a 100 MHz clock on a Xilinx ZCU102 FPGA, outperforming previous work. Furthermore, the code generated by this integration was able to surpass the default hand-tuned schedules provided by the Gemmini developers in real-world workloads.

我们研究自主代理如何学会从不同领域（例如不同环境或不同代理）中的示范中执行任务。这样的跨域模仿学习需要例如从人类专家的演示中培训人造代理。我们提出了一个可扩展的框架，该框架可以实现跨域模仿学习，而无需访问其他演示或进一步的领域知识。我们共同培训学习者的政策，并通过对抗性培训学习学习者和专家领域的映射。我们通过使用共同信息标准来找到包含与任务相关的信息的专家状态空间的嵌入，并且对域细节不变。此步骤大大简化了估计学习者和专家领域之间的映射，因此有助于端到端学习。我们证明了在相当不同的域之间成功转移了政策，而没有额外的示范，以及其他方法失败的情况。

社会机器人的快速发展刺激了人类运动建模，解释和预测，主动碰撞，人类机器人相互作用和共享空间中共同损害的积极研究。现代方法的目标需要高质量的数据集进行培训和评估。但是，大多数可用数据集都遭受了不准确的跟踪数据或跟踪人员的不自然的脚本行为。本文试图通过在语义丰富的环境中提供运动捕获，眼睛凝视跟踪器和板载机器人传感器的高质量跟踪信息来填补这一空白。为了诱导记录参与者的自然行为，我们利用了松散的脚本化任务分配，这使参与者以自然而有目的的方式导航到动态的实验室环境。本文介绍的运动数据集设置了高质量的标准，因为使用语义信息可以增强现实和准确的数据，从而使新算法的开发不仅依赖于跟踪信息，而且还依赖于移动代理的上下文提示，还依赖于跟踪信息。静态和动态环境。

问答（QA）系统越来越多地部署在支持现实世界决策的应用程序中。但是，最新的模型依赖于深层神经网络，这些网络很难被人类解释。固有的可解释模型或事后解释性方法可以帮助用户理解模型如何达到其预测，并在成功的情况下增加对系统的信任。此外，研究人员可以利用这些见解来开发更准确和偏见的新方法。在本文中，我们介绍了Square V2（Square的新版本），以根据图形和基于图形的说明等方法进行比较模型提供解释性基础架构。尽管显着图对于检查每个输入令牌对模型预测的重要性很有用，但来自外部知识图的基于图的解释使用户能够验证模型预测背后的推理。此外，我们提供了多种对抗性攻击，以比较质量检查模型的鲁棒性。通过这些解释性方法和对抗性攻击，我们旨在简化对可信赖的质量检查模型的研究。 Square可在https://square.ukp-lab.de上找到。

在二阶不确定的贝叶斯网络中，条件概率仅在分布中已知，即概率上的概率。Delta方法已应用于扩展精确的一阶推理方法，以通过从贝叶斯网络得出的总和产物网络传播均值和方差，从而表征了认知不确定性或模型本身的不确定性。另外，已经证明了Polytrees的二阶信仰传播，但没有针对一般的定向无环形结构。在这项工作中，我们将循环信念传播扩展到二阶贝叶斯网络的设置，从而产生二阶循环信念传播（SOLBP）。对于二阶贝叶斯网络，SOLBP生成了与Sum-Propoduct网络生成的网络一致的推论，同时更加有效且可扩展。

当历史数据受到限制时，与贝叶斯网络节点相关的条件概率不确定，并且可以在经验上进行估计。二阶估计方法为估计概率和量化这些估计的不确定性提供了一个框架。我们将这些案例称为Uncer Tain或二阶贝叶斯网络。当完成此类数据时，即每个实例化都观察到所有可变值，已知有条件的概率是dirichlet分布的。本文通过使他们能够学习参数（即条件概率），通过不完整的数据来学习不确定的贝叶斯网络的当前最新方法。我们广泛评估各种方法，通过各种查询的置信界的所需和经验得出的强度来学习参数的后验。